Flublok® and Fluzone® High-Dose are vaccines indicated for the prevention of disease caused by influenza A and B strains contained in (or in the case of Flublok, represented by antigens contained in) the vaccine. Flublok is given to individuals 9 years of age and older. Fluzone High-Dose is given to people 65 years of age and older.
Flu-related complications are serious.
Flu-related complications can put older adults at greater risk for hospitalization, pneumonia, or heart attack.
The CDC classified the 2024-2025 flu season as a high-severity season for people of all ages, with the highest flu-related hospitalization rate recorded since the 2010-2011 season.
Hospitalizations from Flu
In a study of almost 1,300 people 40 years or older, some people were approximately 10 times more likely to experience their first heart attack after having the flu.
⁓10X Increased Risk
of Heart
Attack
Fight the flu with Sanofi.
Not all flu vaccines are the same. You do have a choice, so ask for a Sanofi higher-dose flu shot–Fluzone High-Dose and Flublok.
With 4x and 3x more antigen than a regular flu shot, they're proven to provide better flu protection than standard-dose flu shots in older adults. They’ve even been shown to better protect against flu-related complications.*
Find your Sanofi higher-dose flu shot for better protection.
Find Now*See the studies page for full study design of our randomized controlled trials and real-world evidence.
Ask for the Sanofi higher-dose shot for your age.
Get superior protection with Fluzone® High-Dose (Influenza Vaccine).
First and only flu shot clinically proven to provide superior flu protection† in adults 65+.‡
†Compared to Fluzone, the most common side effects were slightly more frequent and included pain at the injection site, muscle ache, tiredness, and headache.
‡In a clinical study conducted in 2011-2012 and 2012-2013 in approximately 32,000 adults 65+, the trivalent formulation proved to be 24% more effective at preventing the flu than standard-dose Fluzone® (Influenza Vaccine).
Studied over 12 flu seasons.
The ability of Fluzone High-Dose to protect those 65+ from flu-related hospitalizations, including hospitalizations due to cardiovascular events and respiratory events, was assessed over 12 flu seasons in comparison to regular flu shots. See the studies that show protection on the See the Studies page.
Fluzone High-Dose is FREE for almost everyone.
See Costs and CoverageDiscover all the benefits of Fluzone High-Dose.
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Get proven protection with Flublok® (Influenza Vaccine).
Clinically proven to provide 30% more protection§ compared to a regular flu shot in adults 50+ that included some patients with comorbidities, like heart disease and diabetes.||
§The safety profile of Flublok was similar to that of the regular flu shot in adults aged 50+. In 50+, the most common side effects with Flublok were tenderness and/or pain where you got the shot, headache, and tiredness.
||A clinical study of approximately 9,000 people 50+ during the 2014-2015 flu season compared Flublok (quadrivalent), with Fluarix® Quadrivalent, standard dose-vaccine. The efficacy of the trivalent and quadrivalent formulations are related because both are made using the same process and have overlapping compositions.
Confidence supported by numbers.
- The largest randomized real-world flu effectiveness study to date (~1.6 million people), Flublok provided better flu protection in adults 50-64 compared to a regular shot. See the studies that support the protection you can trust on the See the Studies page
- Flublok is supported by one of the largest safety studies of a flu vaccine in pregnant women, including about 15,000 patients. For more details, See the Studies page
Flublok is FREE for almost everyone.
Learn MoreDiscover all the benefits of Flublok.
Go NowFind your Sanofi higher-dose flu shot.
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