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A flu vaccine intended for people your age, FLUZONE® HIGH-DOSE QUADRIVALENT helps protect against the flu and the serious flu-related health risks that often come with it.

FLUZONE® HIGH-DOSE QUADRIVALENT—proven to provide superior protection. It has 4x the dose versus standard-dose Fluzone (Influenza Vaccine)

In a clinical study conducted in 2011-2012 and 2012-2013 in approximately 32,000 adults 65+, the trivalent formulation proved to be 24% more effective at preventing the flu than standard-dose Fluzone (Influenza Vaccine).

Compared to Fluzone, the most common side effects were slightly more frequent and included redness at the injection site, muscle ache, tiredness, and headache.

The immune response and side effects of FLUZONE® HIGH-DOSE QUADRIVALENT were similar to the trivalent formulation in a 2017-2018 clinical study in 2,670 adults 65+. FLUZONE® HIGH-DOSE QUADRIVALENT is expected to provide better protection against the flu compared to standard-dose quadrivalent flu vaccines.

FLUZONE® HIGH-DOSE QUADRIVALENT—proven to provide superior protection with 4x the dose versus standard-dose Fluzone (Influenza Vaccine)

In a clinical study conducted in 2011-2012 and 2012-2013 in approximately 32,000 adults 65+, the trivalent formulation proved to be 24% more effective at preventing the flu than standard-dose Fluzone (Influenza Vaccine).

Compared to Fluzone, the most common side effects were slightly more frequent and included redness at the injection site, muscle ache, tiredness, and headache.

The immune response and side effects of FLUZONE® HIGH-DOSE QUADRIVALENT were similar to the trivalent formulation in a 2017-2018 clinical study in 2,670 adults 65+. FLUZONE® HIGH-DOSE QUADRIVALENT is expected to provide better protection against the flu compared to standard-dose quadrivalent flu vaccines.

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You can have confidence in the data

The effectiveness of Fluzone® High-Dose (Influenza Vaccine) has been studied for 10 years across a variety of flu-related complications.

The efficacy of the trivalent and quadrivalent formulations of Fluzone High-Dose (Influenza Vaccine) are related because both are made using the same process and have overlapping compositions.

SEE THE STUDIES

At 65+, your risk of flu and flu-related complications is significantly increased

Factors such as lowered immunity and living with chronic health conditions make getting the flu more likely and more dangerous than when you were younger.

Common chronic conditions increase the risk of developing serious flu-related complications, including respiratory illnesses—such as asthma and chronic obstructive pulmonary disease (COPD)—heart disease, diabetes, and kidney and liver disease

Flu vaccines help reduce your risk of flu and flu-related complications.

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Internal calculations by Sanofi based on IQVIA database of total flu vaccines administered from 8/21-4/22 in people 65+. Study details and information maintained by Sanofi.

What are FLUBLOK® QUADRIVALENT (INFLUENZA VACCINE) and FLUZONE® HIGH-DOSE QUADRIVALENT (INFLUENZA VACCINE)?

Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are indicated for immunization against disease caused by influenza A and B strains contained in the vaccine. Flublok Quadrivalent is given to people 18 years of age and older. Fluzone High-Dose Quadrivalent is given to people 65 years of age and older.

IMPORTANT SAFETY INFORMATION

Flublok Quadrivalent and Fluzone High-Dose Quadrivalent should not be given to anyone who has had a severe allergic reaction to any component of the vaccine (including eggs or egg products for Fluzone High-Dose Quadrivalent). In addition, Fluzone High-Dose Quadrivalent should not be given to anyone who has had a severe allergic reaction after previous dose of any influenza vaccine.

Tell your health care provider if you have ever had Guillain-Barré syndrome (severe muscle weakness) after a previous influenza vaccination.

If Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are given to people with a compromised immune system, including those receiving therapies that suppress the immune system, the immune response may be lower than expected.

Vaccination with Flublok Quadrivalent and Fluzone High-Dose Quadrivalent may not protect all people who receive the vaccine.

For Flublok Quadrivalent, in adults 18 through 49 years of age, the most common side effects were tenderness, and/or pain where you got the shot; headache, tiredness, muscle aches, and joint pain. In adults 50 years of age and older the most common side effects were tenderness, and/or pain where you got the shot; headache, and tiredness.

For Fluzone High-Dose Quadrivalent, in adults 65 years of age and older, the most common side effects were pain, redness, and/or swelling where you got the shot; muscle aches, headache, and general discomfort.

For Flublok Quadrivalent and Fluzone High-Dose Quadrivalent, other side effects may occur.

For more information, talk to your health care professional and refer to the full Prescribing Information for Flublok Quadrivalent or Fluzone High-Dose Quadrivalent. Also, please see complete Patient Information for Fluzone High-Dose Quadrivalent.