FLUBLOK® QUADRIVALENT and FLUZONE® HIGH-DOSE QUADRIVALENT are indicated for immunization against disease caused by influenza A and B strains contained in the vaccine. FLUBLOK® QUADRIVALENT is given to people 18 years of age and older. FLUZONE® HIGH-DOSE QUADRIVALENT is given to people 65 years of age or older.

The flu is more dangerous than you may think

Flu-related complications can happen at any age and can put you at greater risk for hospitalization, pneumonia, or heart attack.

Fight the flu with Sanofi flu vaccines, which help prevent flu in older adults. They’ve even been shown to provide better protection from flu-related complications compared to standard-dose flu shots.

See the studies page for full study design of our randomized controlled trials and real-world evidence.

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Did you know?

In a study of almost 1,300 people 40 years or older, some people were approximately 10 times more likely to experience their first heart attack after having the flu.

Not all flu vaccines are the same.

You do have a choice, so ask for a Sanofi flu vaccine by name.
Get the vaccine for your age.

FLUZONE® HIGH-DOSE
QUADRIVALENT

For adults 65+

  • The #1-used flu vaccine for people 65 and older*
  • Superior flu protection for adults 65 and older versus standard-dose Fluzone® (Influenza Vaccine)
  • In a clinical study conducted in 2011-2012 and 2012-2013 in approximately 32,000 adults 65+, the trivalent formulation proved to be 24% more effective at preventing the flu than standard-dose Fluzone® (Influenza Vaccine)
  • Compared to Fluzone®, the most common side effects were slightly more frequent and included pain and redness at the injection site, muscle ache, tiredness, and headache
  • The immune response and side effects of FLUZONE® HIGH-DOSE QUADRIVALENT were similar to the trivalent formulation in a 2017-2018 clinical study in 2,670 adults 65+. FLUZONE® HIGH-DOSE QUADRIVALENT is expected to provide better protection against the flu compared with standard-dose quadrivalent flu vaccines
  • Formulated specifically for adults 65+, with 4 times the standard-dose flu shot

*

Internal calculations by Sanofi based on IQVIA database of total flu vaccines administered from 8/21-4/22 in people 65+. Study details and information maintained by Sanofi.

FLUBLOK®
QUADRIVALENT

For adults 18+

  • In a clinical study of approximately 8,600 people (about 4,300 in each of 2 groups), FLUBLOK® QUADRIVALENT was proven to be 30% more effective at preventing flu in people 50+ than Fluarix® Quadrivalent (Influenza Vaccine)
  • In adults 50 years of age and older, the most common side effects were pain and/or tenderness at the injection site, headache, and tiredness
  • Has 3 times the standard-dose flu shot

What are FLUBLOK® QUADRIVALENT (INFLUENZA VACCINE) and FLUZONE® HIGH-DOSE QUADRIVALENT (INFLUENZA VACCINE)?

Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are indicated for immunization against disease caused by influenza A and B strains contained in the vaccine. Flublok Quadrivalent is given to people 18 years of age and older. Fluzone High-Dose Quadrivalent is given to people 65 years of age and older.

IMPORTANT SAFETY INFORMATION

Flublok Quadrivalent and Fluzone High-Dose Quadrivalent should not be given to anyone who has had a severe allergic reaction to any component of the vaccine (including eggs or egg products for Fluzone High-Dose Quadrivalent). In addition, Fluzone High-Dose Quadrivalent should not be given to anyone who has had a severe allergic reaction after previous dose of any influenza vaccine.

Tell your health care provider if you have ever had Guillain-Barré syndrome (severe muscle weakness) after a previous influenza vaccination.

If Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are given to people with a compromised immune system, including those receiving therapies that suppress the immune system, the immune response may be lower than expected.

Vaccination with Flublok Quadrivalent and Fluzone High-Dose Quadrivalent may not protect all people who receive the vaccine.

For Flublok Quadrivalent, in adults 18 through 49 years of age, the most common side effects were tenderness, and/or pain where you got the shot; headache, tiredness, muscle aches, and joint pain. In adults 50 years of age and older the most common side effects were tenderness, and/or pain where you got the shot; headache, and tiredness.

For Fluzone High-Dose Quadrivalent, in adults 65 years of age and older, the most common side effects were pain, redness, and/or swelling where you got the shot; muscle aches, headache, and general discomfort.

For Flublok Quadrivalent and Fluzone High-Dose Quadrivalent, other side effects may occur.

For more information, talk to your health care professional and refer to the full Prescribing Information for Flublok Quadrivalent or Fluzone High-Dose Quadrivalent. Also, please see complete Patient Information for Fluzone High-Dose Quadrivalent.